Immunological landscape of nanotechnology-based depression research: a bibliometric analysis of neuroinflammation and immune modulation - Takeaways - MDSpire

Immunological landscape of nanotechnology-based depression research: a bibliometric analysis of neuroinflammation and immune modulation

  • By

  • Zi-yi Guo

  • Jian-hua Zou

  • Yan-chen Feng

  • Zhuo-yu Ren

  • Wen-bin Wang

  • Juan-juan Feng

  • Jie Zhao

  • May 1, 2026

  • 0 min

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  • 1

    Nanotechnology is being explored for its potential to modulate immune responses and address neuroinflammation in depression research.

  • 2

    A bibliometric analysis identified 591 articles, showing significant growth in research post-2020, primarily from China and the United States.

  • 3

    Research themes have shifted from neurotransmitter delivery to a focus on neuroinflammation and immune modulation in depression.

  • 4

    Key topics include microglial biology, oxidative stress, and pro-inflammatory cytokines, indicating evolving research priorities.

  • 5

    This analysis aims to guide future research and clinical applications of immunomodulatory nanomedicine in treating depression.

Original Source(s)

Immunological landscape of nanotechnology-based depression research: a bibliometric analysis of neuroinflammation and immune modulation

  • by Zi-yi Guo, Jian-hua Zou, Yan-chen Feng, Zhuo-yu Ren, Wen-bin Wang, Juan-juan Feng, Jie Zhao

  • May 1, 2026

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