Associations of systemic immune-inflammation index and aggregate index of systemic inflammation with acute gouty arthritis in men: a cross-sectional study - Takeaways - MDSpire

Associations of systemic immune-inflammation index and aggregate index of systemic inflammation with acute gouty arthritis in men: a cross-sectional study

  • By

  • Ziran Xiu

  • Zhengnan Gao

  • Lan Luo

  • Peiyang Yu

  • May 14, 2026

  • 0 min

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  • 1

    The study evaluated the relationship between inflammatory markers and acute gouty arthritis (AGA) in 380 male participants.

  • 2

    Significant associations were found between AGA and inflammatory markers such as MLR, NLR, PLR, SII, SIRI, and AISI.

  • 3

    Nonlinear dose–response relationships were identified between SII and AGA, as well as between AISI and AGA.

  • 4

    Subgroup analysis indicated that inflammatory markers were more effective in assessing AGA in men with fatty liver.

  • 5

    SII and AISI demonstrated superior diagnostic accuracy compared to other inflammatory markers for assessing AGA risk.

Original Source(s)

Associations of systemic immune-inflammation index and aggregate index of systemic inflammation with acute gouty arthritis in men: a cross-sectional study

  • by Ziran Xiu, Zhengnan Gao, Lan Luo, Peiyang Yu

  • May 14, 2026

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