Empowering Patient Perspectives in Influenza Research and Management: A Comprehensive Review of Patient-Reported Outcomes - Takeaways - MDSpire

Empowering Patient Perspectives in Influenza Research and Management: A Comprehensive Review of Patient-Reported Outcomes

  • By

  • Elizabeth Meda-Monzón

  • Paloma Muñoz-Aguirre

  • Barbara Aída Flores-Aldana

  • Chad Gwaltney

  • José Bartelt-Hofer

  • February 21, 2026

  • 0 min

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  • 1

    Influenza causes significant morbidity and mortality worldwide, with an estimated 294,000 to 518,000 deaths annually.

  • 2

    Patient-reported outcomes (PROs) capture patients' perspectives on health, enhancing personalized care and informing public health decisions.

  • 3

    Generic PRO instruments may overlook disease-specific attributes, necessitating targeted measures for accurate evaluation of interventions.

  • 4

    This study reviews PRO instruments for influenza, identifying gaps and providing recommendations for their effective implementation in research.

  • 5

    A systematic literature review was conducted to assess the utilization of PROs in influenza research, focusing on psychometric validation and regulatory guidelines.

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