Assessing HIV Vulnerability and the Use of Oral Pre-Exposure Prophylaxis (PrEP) in Injecting Drug Users in Nairobi: A Cross-Sectional Analysis - Takeaways - MDSpire

Assessing HIV Vulnerability and the Use of Oral Pre-Exposure Prophylaxis (PrEP) in Injecting Drug Users in Nairobi: A Cross-Sectional Analysis

  • By

  • Cosmas Mugambi

  • Loice Mbogo

  • William Sinkele

  • Esther Gitau

  • Tecla Temu

  • Carey Farquhar

  • David Bukusi

  • John Kinuthia

  • Aliza Monroe-Wise

  • January 5, 2026

  • 0 min

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  • 1

    HIV prevalence among people who inject drugs (PWID) in Kenya was estimated at 18.7% in 2021, highlighting significant health disparities.

  • 2

    Pre-exposure prophylaxis (PrEP) can reduce HIV acquisition risk by 99% from sex and 74% from drug injection, yet awareness among PWID remains low.

  • 3

    Provider-level barriers, including stigma and misconceptions about drug users, contribute to the low uptake of PrEP among PWID in Kenya.

  • 4

    The study aimed to assess HIV vulnerability and PrEP knowledge among PWID in Nairobi, addressing gaps in research and intervention strategies.

  • 5

    Improving PrEP uptake among PWID requires understanding their specific risks and needs, as current outreach efforts primarily target other key populations.

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