Case report: A case of adolescent invasive encapsulated follicular variant of papillary thyroid carcinoma with literature review - Takeaways - MDSpire
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Clinical Case Study: Adolescent Patient with Invasive Encapsulated Follicular Variant of Papillary Thyroid Carcinoma and Review of Existing Literature

  • By

  • Wenxuan Zhang

  • Nina Qu

  • June 30, 2026

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  • 1

    Invasive Encapsulated Follicular Variant of Papillary Thyroid Carcinoma (IEFVPTC) is recognized as an independent entity in the 2022 WHO classification.

  • 2

    A 13-year-old female patient presented with a neck mass, and ultrasound revealed a 3.4 cm hypoechoic nodule classified as TI-RADS 4a.

  • 3

    The patient underwent total endoscopic transaxillary left thyroid lobectomy, and pathology confirmed minimally invasive IEFVPTC.

  • 4

    IEFVPTC may present with benign ultrasound features, necessitating heightened vigilance and potential needle biopsy in adolescents.

  • 5

    Surgical extent for IEFVPTC should be tailored to invasiveness, focusing on distant metastasis screening due to its hematogenous spread.

Original Source(s)

Case report: A case of adolescent invasive encapsulated follicular variant of papillary thyroid carcinoma with literature review

  • by Wenxuan Zhang, Nina Qu

  • June 30, 2026

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