Morphological Changes in the Cornea Following Cessation of Long-Term Orthokeratology and Outcomes of SMILE Surgery: A Retrospective Comparative Analysis - Takeaways - MDSpire

Morphological Changes in the Cornea Following Cessation of Long-Term Orthokeratology and Outcomes of SMILE Surgery: A Retrospective Comparative Analysis

  • By

  • Kun Zhou

  • Xiaohuan Ma

  • Di Shen

  • Wenjia Cao

  • Xiyu Sun

  • Mengchen Li

  • Wei Wei

  • February 13, 2026

  • 0 min

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  • 1

    Myopia is a significant public health issue, particularly in East Asia, with over 80% of adolescents in China affected.

  • 2

    Orthokeratology (OK) is widely used for myopia control, involving overnight wear of rigid lenses to temporarily flatten the cornea.

  • 3

    The study analyzed 44 eyes, comparing 22 former OK users to 22 control patients, assessing corneal changes after lens cessation.

  • 4

    Results indicated potential residual corneal changes in OK users, including flattening and increased astigmatism, impacting SMILE outcomes.

  • 5

    Statistical analyses confirmed significant differences in corneal morphology and visual outcomes between the OK and control groups post-SMILE.

Original Source(s)

Morphological Changes in the Cornea Following Cessation of Long-Term Orthokeratology and Outcomes of SMILE Surgery: A Retrospective Comparative Analysis

  • by Kun Zhou, Xiaohuan Ma, Di Shen, Wenjia Cao, Xiyu Sun, Mengchen Li, Wei Wei

  • February 13, 2026

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