Visit-to-visit HbA1c variability and subsequent renal function decline in older adults with type 2 diabetes - Takeaways - MDSpire

Visit-to-visit HbA1c variability and subsequent renal function decline in older adults with type 2 diabetes

  • By

  • Tianchi Hu

  • Xueqin Chen

  • Yi Zhou

  • Lin Lin

  • Wanzhang Li

  • Yanjing Fan

  • June 23, 2026

  • 0 min

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  • 1

    The study assessed the association between visit-to-visit HbA1c variability and renal function decline in older adults with type 2 diabetes.

  • 2

    A total of 630 participants aged ≥65 years were enrolled, with a median follow-up of 4.6 years.

  • 3

    Each 5% increase in HbA1c coefficient of variation was linked to a higher risk of renal decline (HR 1.19, p < 0.001).

  • 4

    Participants in the highest tertile of HbA1c variability had a significantly increased risk of renal decline (HR 1.58, p = 0.002).

  • 5

    The study highlights that greater HbA1c variability is independently associated with renal function decline in older adults with diabetes.

Original Source(s)

Visit-to-visit HbA1c variability and subsequent renal function decline in older adults with type 2 diabetes

  • by Tianchi Hu, Xueqin Chen, Yi Zhou, Lin Lin, Wanzhang Li, Yanjing Fan

  • June 23, 2026

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