Inhaled budesonide and beclomethasone for the prevention and treatment of bronchopulmonary dysplasia in very preterm infants: a prospective randomized controlled trial - Takeaways - MDSpire

Inhaled budesonide and beclomethasone for the prevention and treatment of bronchopulmonary dysplasia in very preterm infants: a prospective randomized controlled trial

  • By

  • Bingjie Wang

  • Siyuan Xu

  • Zheng Li

  • Kaidong Yang

  • Nuo Xu

  • Di Huang

  • Dandan Zhao

  • Bo Yang

  • Xiangyu Gao

  • June 4, 2026

  • 0 min

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  • 1

    Inhaled budesonide and beclomethasone were evaluated for preventing and treating bronchopulmonary dysplasia (BPD) in very preterm infants.

  • 2

    Both inhaled corticosteroids significantly shortened the duration of respiratory support compared to the control group without increasing adverse outcomes.

  • 3

    No significant differences were found in the incidence or severity of BPD among the three groups, indicating similar efficacy.

  • 4

    Younger gestational age and lower birth weight were identified as independent risk factors for BPD, while inhaled corticosteroids served as protective factors.

  • 5

    The study concluded that inhaled budesonide and beclomethasone are safe and effective for reducing respiratory support duration in high-risk preterm infants.

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