Association between urinary hCG trajectories and the risk of miscarriage in women undergoing embryo transfer: a prospective cohort study - Takeaways - MDSpire

Association between urinary hCG trajectories and the risk of miscarriage in women undergoing embryo transfer: a prospective cohort study

  • By

  • Jing Wang

  • Xin Wang

  • Liming Wang

  • Xiao Zhang

  • Pengfei Zang

  • Wenlong Han

  • Lu Chen

  • Qingkai Wang

  • Yi Li

  • Liyi Cai

  • June 4, 2026

  • 0 min

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  • 1

    This study analyzed the relationship between urinary hCG patterns and miscarriage risk in women undergoing embryo transfer.

  • 2

    Three distinct urinary hCG trajectories were identified: Low-Slow, Low-Steady, and High-Steady.

  • 3

    The Low-Slow trajectory was associated with a significantly higher miscarriage risk compared to the High-Steady trajectory.

  • 4

    The predictive model for miscarriage risk achieved an AUC of 0.857, indicating strong predictive performance.

  • 5

    Early recognition of abnormal hCG dynamics may enhance risk stratification and personalized management in IVF-ET.

Original Source(s)

Association between urinary hCG trajectories and the risk of miscarriage in women undergoing embryo transfer: a prospective cohort study

  • by Jing Wang, Xin Wang, Liming Wang, Xiao Zhang, Pengfei Zang, Wenlong Han, Lu Chen, Qingkai Wang, Yi Li, Liyi Cai

  • June 4, 2026

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