A novel marker for predicting malignancy in patients with thyroid nodules diagnosed as AUS on initial cytology: thyroid hormone sensitivity - Takeaways - MDSpire

A novel marker for predicting malignancy in patients with thyroid nodules diagnosed as AUS on initial cytology: thyroid hormone sensitivity

  • By

  • Puren Gokbulut

  • Cagatay Emir Onder

  • Serife Mehlika Kuskonmaz

  • Huseyin Yagcı

  • Cavit Culha

  • Gonul Koc

  • May 12, 2026

  • 0 min

Share

  • 1

    Thyroid hormone sensitivity indices and inflammatory markers can predict malignancy in thyroid nodules classified as AUS.

  • 2

    In a study of 415 thyroid nodules, 30.8% were found to be malignant after surgical treatment.

  • 3

    Malignant nodules exhibited higher rates of solid composition, hypoechogenicity, and irregular margins compared to benign nodules.

  • 4

    Family history of thyroid cancer was significantly more common in the malignant group, indicating a potential risk factor.

  • 5

    Thyroid hormone sensitivity indices may enhance risk stratification and complement ultrasonographic assessments in clinical decision-making.

Original Source(s)

A novel marker for predicting malignancy in patients with thyroid nodules diagnosed as AUS on initial cytology: thyroid hormone sensitivity

  • by Puren Gokbulut, Cagatay Emir Onder, Serife Mehlika Kuskonmaz, Huseyin Yagcı, Cavit Culha, Gonul Koc

  • May 12, 2026

Related Content

A Novel Interpretable Machine Learning Method for Predicting Distant Metastasis in Papillary Thyroid Carcinoma: Development, Validation, and Clinical Implications

Advanced age and differentiated thyroid carcinoma: a retrospective cohort study investigating surgical outcomes and recurrence risk

Longitudinal dynamics of symptom networks in patients with differentiated thyroid cancer undergoing radioactive iodine therapy: a prospective cohort study