Nearly one in five heart failure patients had a history of cancer diagnosed over two years prior to heart failure onset.
2
Patients with heart failure and prior malignancy faced higher all-cause mortality but similar cardiovascular death rates compared to those without malignancy.
3
A distinct echocardiographic phenotype linked to cardiac wasting was identified in advanced cancer patients, showing reduced left ventricular mass.
4
Low-dose sacubitril/valsartan reduced cancer therapy-related cardiac dysfunction incidence in breast cancer patients compared to standard care.
5
High-volume centers for cardiogenic shock treatment were associated with lower in-hospital mortality, supporting regionalized care models.
Despite major advances in guideline-directed medical therapy (GDMT), worsening heart failure continues to drive significant morbidity, repeat hospitalizations and healthcare utilization worldwide.
