Case Report: A rare triad of neoplasms: navigating synchronous accessory breast cancer, papillary thyroid carcinoma, and inflammatory nasal papilloma

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A 60-year-old woman presented with a left axillary mass, diagnosed as grade II invasive ductal carcinoma of accessory breast origin.
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Concurrent evaluations revealed a papillary thyroid carcinoma and a benign nasal papilloma, complicating the clinical management.
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The patient underwent neoadjuvant chemotherapy followed by sequential surgeries for the accessory breast cancer, thyroid carcinoma, and nasal papilloma.
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Final pathology confirmed three distinct primary tumors, necessitating a multidisciplinary approach for effective treatment.
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This case highlights the importance of considering accessory breast carcinoma in differential diagnoses of isolated axillary masses.

Frontiers In Medicine

by Xiangning Zeng, Huang Huang, Yuzhong Hong, Qin Meng, Kaihua Ye, Lian Zhou, Huajun Li, Ying Chen, Jiawei Huang, Chuxia Feng
June 1, 2026

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