Association of TyG index with sepsis incidence and mortality: a prospective study with diabetes stratification - Takeaways - MDSpire

Association of TyG index with sepsis incidence and mortality: a prospective study with diabetes stratification

  • By

  • Shuying You

  • Zhenhua Xing

  • Jiaqing Hu

  • May 28, 2026

  • 0 min

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  • 1

    The study analyzed 428,207 participants to assess the relationship between the TyG index and sepsis risk and mortality.

  • 2

    A linear association between the TyG index and sepsis outcomes was found in diabetic individuals, while a U-shaped association was observed in non-diabetics.

  • 3

    Each 1-unit increase in the TyG index correlated with an 18% higher risk of sepsis and a 16% higher risk of sepsis-related mortality in the diabetic subgroup.

  • 4

    No significant associations were found between the TyG index and sepsis outcomes in non-diabetic participants.

  • 5

    The findings suggest the TyG index may be a useful biomarker for sepsis risk stratification in diabetic patients, warranting further validation.

Original Source(s)

Association of TyG index with sepsis incidence and mortality: a prospective study with diabetes stratification

  • by Shuying You, Zhenhua Xing, Jiaqing Hu

  • May 28, 2026

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