Risk of macrovascular events among patients with ICD-defined neuromyelitis optica in Taiwan - Takeaways - MDSpire

Risk of macrovascular events among patients with ICD-defined neuromyelitis optica in Taiwan

  • By

  • Chih-Jaan Tai

  • Kuang-Hua Huang

  • Tsuei-Hung Wang

  • Tung-Han Tsai

  • Shuo-Yan Gau

  • Vincent Ping-Sheng Lai

  • Zheng-Ren Lin

  • Chien-Ying Lee

  • July 1, 2026

  • 0 min

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  • 1

    Patients with ICD-defined Neuromyelitis Optica (NMO) have a significantly higher risk of cardiovascular disease (CVD) compared to matched controls.

  • 2

    The study found an adjusted hazard ratio of 1.40 for CVD and 3.37 for cerebrovascular disease (CBD) in patients with NMO.

  • 3

    Significant associations were noted between NMO and ischemic stroke, hemorrhagic stroke, and transient ischemic attack.

  • 4

    NMO was not associated with an increased risk of acute myocardial infarction, atrial fibrillation, coronary artery disease, or heart failure.

  • 5

    This research utilized a retrospective cohort design based on data from Taiwan's National Health Insurance Research Database.

Original Source(s)

Risk of macrovascular events among patients with ICD-defined neuromyelitis optica in Taiwan

  • by Chih-Jaan Tai, Kuang-Hua Huang, Tsuei-Hung Wang, Tung-Han Tsai, Shuo-Yan Gau, Vincent Ping-Sheng Lai, Zheng-Ren Lin, Chien-Ying Lee

  • July 1, 2026

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