Is creatine kinase a valid aid in early cardiac muscle damage detection during treatment for childhood acute lymphoblastic leukemia? A case report - Takeaways - MDSpire

Is creatine kinase a valid aid in early cardiac muscle damage detection during treatment for childhood acute lymphoblastic leukemia? A case report

  • By

  • Grazia Fazio

  • Jari Intra

  • Orsola Montini

  • Laura Rachele Bettini

  • Giacomo Gotti

  • Alessandra Sala

  • Silvia Bungaro

  • Giovanni Cazzaniga

  • Carmelo Rizzari

  • Adriana Balduzzi

  • Marco Casati

  • May 1, 2026

  • 0 min

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  • 1

    Creatine kinase (CK) is a crucial enzyme found in high levels in skeletal muscle and myocardium, serving as a potential biomarker for cardiac injury.

  • 2

    The study focuses on a pediatric patient with acute lymphoblastic leukemia who exhibited elevated CK levels during chemotherapy.

  • 3

    Elevated CK levels can indicate muscle injury and have been associated with cardiotoxicity from chemotherapeutic agents.

  • 4

    The case highlights the importance of monitoring CK levels for early detection of cardiac muscle injury in pediatric cancer patients.

  • 5

    The findings suggest that CK may be a viable biomarker for assessing cardiac health during chemotherapy in children with ALL.

Original Source(s)

Is creatine kinase a valid aid in early cardiac muscle damage detection during treatment for childhood acute lymphoblastic leukemia? A case report

  • by Grazia Fazio, Jari Intra, Orsola Montini, Laura Rachele Bettini, Giacomo Gotti, Alessandra Sala, Silvia Bungaro, Giovanni Cazzaniga, Carmelo Rizzari, Adriana Balduzzi, Marco Casati

  • May 1, 2026

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