Variations in Lung Parenchyma Attenuation Following Contrast Use in Quantitative Dual Energy Chest CT - Takeaways - MDSpire

Variations in Lung Parenchyma Attenuation Following Contrast Use in Quantitative Dual Energy Chest CT

  • By

  • Christina Schachner

  • Quirin D. Strotzer

  • Lucca Scheuermeyer

  • Sonja Frank

  • Florian Raab

  • Stefanie Meiler

  • Maximilian V. Malfertheiner

  • Simone Hammer

  • Christian Stroszczynski

  • Okka W. Hamer

  • April 16, 2026

  • 0 min

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  • 1

    Contrast administration during chest CT increases lung parenchymal density, potentially leading to misinterpretations in radiological assessments.

  • 2

    This study aims to analyze regional variations in lung density after contrast use compared to true non-contrast and virtual non-contrast images.

  • 3

    Forty-eight patients were included, with a median age of 63 years, primarily suffering from emphysema or overinflation.

  • 4

    The study utilized advanced imaging techniques, including dual-energy CT and machine learning for lung segmentation and analysis.

  • 5

    Statistical methods such as Bland-Altman analysis and Mann-Whitney-U tests were employed to evaluate differences in lung density measurements.

Original Source(s)

Variations in Lung Parenchyma Attenuation Following Contrast Use in Quantitative Dual Energy Chest CT

  • by Christina Schachner, Quirin D. Strotzer, Lucca Scheuermeyer, Sonja Frank, Florian Raab, Stefanie Meiler, Maximilian V. Malfertheiner, Simone Hammer, Christian Stroszczynski, Okka W. Hamer

  • April 16, 2026

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