Impact of Aerobic versus Resistance Training on Sleep Quality and Cancer-Related Fatigue in Breast Cancer Patients Undergoing Neoadjuvant Chemotherapy: A Three-Arm Randomized Controlled Study - Takeaways - MDSpire

Impact of Aerobic versus Resistance Training on Sleep Quality and Cancer-Related Fatigue in Breast Cancer Patients Undergoing Neoadjuvant Chemotherapy: A Three-Arm Randomized Controlled Study

  • By

  • Alexander Haussmann

  • Martina E. Schmidt

  • Siri Goldschmidt

  • Anouk E. Hiensch

  • Joachim Wiskemann

  • Karen Steindorf

  • January 28, 2026

  • 0 min

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  • 1

    Breast cancer is the most common cancer in women, with significant prevalence and impact on health, particularly during neoadjuvant chemotherapy.

  • 2

    Neoadjuvant chemotherapy can lead to cancer-related fatigue and sleep disturbances, which are distressing symptoms for patients.

  • 3

    Exercise interventions, particularly aerobic and resistance training, may alleviate cancer-related fatigue and improve sleep quality during treatment.

  • 4

    The BENEFIT trial is a three-arm randomized controlled trial comparing the effects of aerobic and resistance training during neoadjuvant chemotherapy.

  • 5

    This study aims to determine the optimal timing and type of exercise intervention to manage fatigue and sleep disturbances in breast cancer patients.

Original Source(s)

Impact of Aerobic versus Resistance Training on Sleep Quality and Cancer-Related Fatigue in Breast Cancer Patients Undergoing Neoadjuvant Chemotherapy: A Three-Arm Randomized Controlled Study

  • by Alexander Haussmann, Martina E. Schmidt, Siri Goldschmidt, Anouk E. Hiensch, Joachim Wiskemann, Karen Steindorf

  • January 28, 2026

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