Noninvasive Evaluation of Ki-67 Overexpression in Breast Cancer Using Ultrasound Radiomics and Habitat Analysis - Takeaways - MDSpire

Noninvasive Evaluation of Ki-67 Overexpression in Breast Cancer Using Ultrasound Radiomics and Habitat Analysis

  • By

  • Li Zhu

  • Shanni Dong

  • Xushuang Qin

  • Xiaoying Mi

  • Jiaqi Zhang

  • Xiaoshu Zhu

  • Yuting Liu

  • Jiake Hua

  • Shuangxi Chen

  • April 29, 2026

  • 0 min

Share

  • 1

    The study developed a nomogram integrating ultrasound radiomics and habitat analysis to predict Ki-67 expression in breast cancer non-invasively.

  • 2

    The Clinics_Habitat_Radiomics model achieved AUCs of 0.877 in training and 0.830 in validation, outperforming conventional models.

  • 3

    Calibration curves showed strong agreement between predicted probabilities and observed outcomes, indicating model reliability.

  • 4

    This approach enhances tumor biology assessment and supports personalized treatment strategies by capturing intratumoral heterogeneity.

  • 5

    The study highlights the potential of ultrasound-based habitat imaging as a robust, accessible imaging biomarker for Ki-67 expression.

Original Source(s)

Noninvasive Evaluation of Ki-67 Overexpression in Breast Cancer Using Ultrasound Radiomics and Habitat Analysis

  • by Li Zhu, Shanni Dong, Xushuang Qin, Xiaoying Mi, Jiaqi Zhang, Xiaoshu Zhu, Yuting Liu, Jiake Hua, Shuangxi Chen

  • April 29, 2026

Related Content

When should you get a mammogram? Conflicting advice makes it hard to know

MIT president: Why so many optimistic scientists are losing heart

Lactylation-mediated remodelling of the breast cancer microenvironment: single-cell multidimensional analysis and prognostic model construction