Case Report: A rare case of ocular giant cell arteritis with bilateral orbital inflammation and diagnostic challenges - Takeaways - MDSpire

Case Report: A rare case of ocular giant cell arteritis with bilateral orbital inflammation and diagnostic challenges

  • By

  • Alexandru N. Lerint

  • Oreoluwa E. Morakinyo

  • Jae Won Oh

  • Vijaya Lakshmi Valaparla

  • Xiangping Li

  • June 9, 2026

  • 0 min

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  • 1

    Giant cell arteritis (GCA) is a systemic vasculitis that can lead to vision loss if untreated, commonly presenting with headaches and scalp tenderness.

  • 2

    Bilateral orbital inflammation in GCA is rare and often underrecognized, with fewer than 10 documented cases of perioptic or retrobulbar infiltration.

  • 3

    A 75-year-old male presented with episodic vision loss and headaches, ultimately diagnosed with GCA after a positive temporal artery biopsy.

  • 4

    Neuroimaging revealed bilateral retrobulbar/perioptic soft-tissue infiltration, highlighting the diagnostic value of MRI in atypical GCA presentations.

  • 5

    The case emphasizes the need for improved diagnostic criteria and the potential role of steroid-sparing agents in managing GCA complications.

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