Tirofiban After Tenecteplase in Stroke - Takeaways - MDSpire
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Tirofiban After Tenecteplase in Stroke

Adjunctive tirofiban was associated with higher rates of excellent 90-day outcomes after inadequate tenecteplase response in selected stroke patients, though adjusted analyses were not significant.

  • By

  • Kathryn Wighton

  • May 14, 2026

  • 6 min

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  • 1

    Tirofiban may improve outcomes post-tenecteplase in stroke patients.

  • 2

    64% of tirofiban patients achieved excellent outcomes vs. 52% with placebo.

  • 3

    No significant statistical differences in secondary outcomes.

  • 4

    Early administration within 4-24 hours post-tenecteplase is crucial.

  • 5

    Trial limited to Chinese population, raising generalizability concerns.

Original Source(s)

Tirofiban After Tenecteplase in Stroke

  • by Kathryn Wighton

  • May 14, 2026

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