Mpox Sequelae Persist 11 to 18 Months After Infection  - Takeaways - MDSpire

Mpox Sequelae Persist 11 to 18 Months After Infection 

  • By

  • Henry Thomas

  • January 27, 2026

  • 3 min

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  • 1

    Over half of adults evaluated 11 to 18 months post-mpox diagnosis had at least one persistent physical sequela.

  • 2

    The most common sequelae were mild appearance-related changes, including skin discoloration and scarring.

  • 3

    Thirteen percent of participants reported functional complications, primarily involving anorectal and urinary symptoms.

  • 4

    Nearly half of participants experienced ongoing social challenges, with significant effects on sexual performance reported.

  • 5

    Persistent sequelae were linked to markers of more severe acute disease, particularly confluent lesions over 2 cm.

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