Myocardial function recovery in peripartum cardiomyopathy: the role of global longitudinal strain and myocardial work - Takeaways - MDSpire
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Recovery of Myocardial Function in Peripartum Cardiomyopathy: Insights from Global Longitudinal Strain and Myocardial Work Analysis

  • By

  • Federica Ilardi

  • Federica Carusone

  • Dario D’Alconzo

  • Rachele Manzo

  • Alessia Palmentieri

  • Ciro Battaglia

  • Dalila Nappa

  • Giuseppe Giugliano

  • Raffaella Lombardi

  • Santo Dellegrottaglie

  • Viviana Narciso

  • Roberta Paolillo

  • Luca Bardi

  • Francesco S. Loffredo

  • Daniele Masarone

  • Enrica Pezzullo

  • Francesca Lanni

  • Donato Gerardi

  • Eugenio Stabile

  • Angelicarosa Cascone

  • Nouha Azaza

  • Giovanni Peretto

  • Giuseppe Bifulco

  • Attilio Di Spiezio Sardo

  • Gabriele Saccone

  • Alaide Chieffo

  • Cinzia Perrino

  • Giovanni Esposito

  • August 26, 2026

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  • 1

    Peripartum cardiomyopathy (PPCM) is characterized by left ventricular systolic dysfunction occurring during or after pregnancy.

  • 2

    In a study of 22 women with PPCM, 72.7% showed recovery of left ventricular ejection fraction (LVEF) after the acute phase.

  • 3

    Groups with LVEF <50% exhibited significantly poorer global longitudinal strain (GLS) and myocardial work (MW) parameters compared to controls.

  • 4

    Even with LVEF recovery, women with PPCM demonstrated lower GLS and global work efficiency (GWE) than healthy controls.

  • 5

    GLS and MW indices may reveal persistent myocardial impairment in PPCM patients, indicating subclinical dysfunction despite normal LVEF.

Original Source(s)

Myocardial function recovery in peripartum cardiomyopathy: the role of global longitudinal strain and myocardial work

  • by Federica Ilardi, Federica Carusone, Dario D’Alconzo, Rachele Manzo, Alessia Palmentieri, Ciro Battaglia, Dalila Nappa, Giuseppe Giugliano, Raffaella Lombardi, Santo Dellegrottaglie, Viviana Narciso, Roberta Paolillo, Luca Bardi, Francesco S. Loffredo, Daniele Masarone, Enrica Pezzullo, Francesca Lanni, Donato Gerardi, Eugenio Stabile, Angelicarosa Cascone, Nouha Azaza, Giovanni Peretto, Giuseppe Bifulco, Attilio Di Spiezio Sardo, Gabriele Saccone, Alaide Chieffo, Cinzia Perrino, Giovanni Esposito

  • August 26, 2026

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