Risk factors for postoperative adverse outcomes in patients with high anal fistula undergoing modified TROPIS procedure combined with Parks’ fistulotomy with seton: a retrospective study - Takeaways - MDSpire

Risk factors for postoperative adverse outcomes in patients with high anal fistula undergoing modified TROPIS procedure combined with Parks’ fistulotomy with seton: a retrospective study

  • By

  • Benfan Yin

  • Jiaying Li

  • Buqiang Chen

  • Xingwang Liang

  • June 1, 2026

  • 0 min

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  • 1

    The study analyzed 218 patients undergoing modified TROPIS with Parks’ fistulotomy and seton for high anal fistula from May 2022 to May 2024.

  • 2

    Postoperative adverse outcomes occurred in 22.5% of patients, including recurrence (8.3%), incontinence (6.9%), delayed healing (10.1%), and major complications (3.7%).

  • 3

    Five independent risk factors for adverse outcomes were identified: diabetes mellitus, horseshoe extension, internal sphincter incision >50%, operative time >60 min, and BMI ≥ 28 kg/m2.

  • 4

    The risk stratification model indicated that 31.2% of patients were high-risk, with an adverse outcome rate of 41.2% compared to 14.0% in low-risk patients.

  • 5

    The findings highlight the need for external validation in larger cohorts before clinical implementation of the modified TROPIS approach.

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