Prevalence of schizophrenia spectrum and bipolar disorder among patients with cannabis induced psychosis: a systematic review and meta-analysis - Takeaways - MDSpire

Prevalence of schizophrenia spectrum and bipolar disorder among patients with cannabis induced psychosis: a systematic review and meta-analysis

  • By

  • Mohammad Saad Javed

  • Rayane El-Khoury

  • Amr Ahmed Taha

  • Shuja Mohd Reagu

  • February 9, 2026

  • 0 min

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  • 1

    Cannabis-induced psychosis (CIP) is associated with a significant risk of developing schizophrenia spectrum disorders (SSD) post-diagnosis.

  • 2

    Approximately 34% of patients with CIP are later diagnosed with SSD, highlighting the need for potential reclassification of CIP.

  • 3

    Patients with CIP also exhibit a higher likelihood of developing bipolar disorder (BD) compared to matched controls.

  • 4

    The study aims to provide updated pooled rates of SSD and BD diagnoses among patients initially diagnosed with CIP.

  • 5

    Methodological limitations in previous studies necessitate a systematic review to clarify the relationship between CIP, SSD, and BD.

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