Creation and assessment of a predictive model for recurrence in postoperative patients with stage ⅠA1-ⅢA non-small cell lung carcinoma - Takeaways - MDSpire

Creation and assessment of a predictive model for recurrence in postoperative patients with stage ⅠA1-ⅢA non-small cell lung carcinoma

  • By

  • Yi Li

  • Renjie Xu

  • Jinghong Xian

  • Zhoufeng Wang

  • Wang Chen

  • Weimin Li

  • November 27, 2025

  • 0 min

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  • 1

    Lung cancer is the leading cause of cancer incidence and mortality globally, with non-small cell lung cancer (NSCLC) accounting for over 85% of cases.

  • 2

    The study aims to develop a multi-dimensional predictive model for postoperative recurrence in stage ⅠA1-ⅢA NSCLC patients using a nomogram.

  • 3

    The model integrates demographic, clinical, pathological, radiological, and genetic data to enhance personalized risk stratification.

  • 4

    A total of 911 NSCLC cases were included, with a follow-up loss rate of 14%, which did not significantly impact the study results.

  • 5

    The study employs LASSO regression and cross-validation to identify influential variables for predicting recurrence in NSCLC patients.

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