Diagnosis and Management of Visceral Leishmaniasis in Children: A French Retrospective Study - Takeaways - MDSpire

Diagnosis and Management of Visceral Leishmaniasis in Children: A French Retrospective Study

  • By

  • Justine de Larminat

  • Naïma Dahane

  • Nicolas Argy

  • Mahmoud Rifai

  • Olivier Haas Ferrua

  • Christelle Pomares

  • Nicolas Rasandisona Ravonjena

  • Damien Dupont

  • Jean-Philippe Lemoine

  • Sarah Dutron

  • Olivia Pineau

  • Philippe Picherit Steinbrucker

  • Thibault César

  • Séhomi Azohana

  • Sophie Guilmin-Crepon

  • Philippe Minodier

  • Irina Allouche

  • Mathie Lorrot

  • Christophe Ravel

  • Albert Faye

  • November 20, 2025

  • 0 min

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  • 1

    The study analyzed 63 pediatric visceral leishmaniasis cases in France from 2012 to 2022, highlighting its rarity in high-income countries.

  • 2

    The median age of affected children was 2 years, with a male-to-female ratio of 1.25, and 57.1% had autochthonous visceral leishmaniasis.

  • 3

    Common symptoms included fever (92%) and splenomegaly (78%), with significant biological findings such as inflammatory syndrome and pancytopenia.

  • 4

    Diagnosis was optimized using combined blood and bone marrow PCR, achieving 100% positivity in patients who underwent both tests.

  • 5

    All patients were treated with liposomal amphotericin B, and while 6.3% relapsed, all children ultimately recovered.

Original Source(s)

Diagnosis and Management of Visceral Leishmaniasis in Children: A French Retrospective Study

  • by Justine de Larminat, Naïma Dahane, Nicolas Argy, Mahmoud Rifai, Olivier Haas Ferrua, Christelle Pomares, Nicolas Rasandisona Ravonjena, Damien Dupont, Jean-Philippe Lemoine, Sarah Dutron, Olivia Pineau, Philippe Picherit Steinbrucker, Thibault César, Séhomi Azohana, Sophie Guilmin-Crepon, Philippe Minodier, Irina Allouche, Mathie Lorrot, Christophe Ravel, Albert Faye

  • November 20, 2025

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