Radiographic sclerosis with intraoperative fragile bone in skeletal fluorosis: a case report - Takeaways - MDSpire

Radiographic sclerosis with intraoperative fragile bone in skeletal fluorosis: a case report

  • By

  • Weikun Hou

  • Lin Liu

  • Wensen Jing

  • Chao Lu

  • Yangquan Hao

  • March 31, 2026

  • 0 min

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  • 1

    Skeletal fluorosis is a rare toxic osteopathy caused by prolonged fluoride exposure, leading to significant bone changes.

  • 2

    A 59-year-old woman with skeletal fluorosis underwent staged bilateral total knee arthroplasty, revealing severe osteoporosis intraoperatively.

  • 3

    Preoperative radiographs indicated increased bone density, but intraoperative findings showed thin cortical bone and sparse trabecular structure.

  • 4

    Clinicians must evaluate bone quality and soft tissue flexibility preoperatively in patients from endemic areas to avoid misdiagnosis.

  • 5

    Postoperative outcomes were positive, with significant improvements in knee function and pain relief after total knee arthroplasties.

Original Source(s)

Radiographic sclerosis with intraoperative fragile bone in skeletal fluorosis: a case report

  • by Weikun Hou, Lin Liu, Wensen Jing, Chao Lu, Yangquan Hao

  • March 31, 2026

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