Associations between vaginal microecological status and high-risk human papillomavirus positivity in women from Eastern China: a retrospective cross-sectional study - Takeaways - MDSpire

Associations between vaginal microecological status and high-risk human papillomavirus positivity in women from Eastern China: a retrospective cross-sectional study

  • By

  • Junxia Wang

  • Xinyong Liu

  • Fangfei Liu

  • Juan Liu

  • Yan Zhao

  • Cuizhu Ma

  • Lina Wang

  • Xing Shi

  • July 10, 2026

  • 0 min

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  • 1

    The study analyzed 14,359 women to assess the relationship between vaginal microecological status and high-risk human papillomavirus (hrHPV) infection.

  • 2

    Overall hrHPV positivity was 15.99%, with the highest rate of 35.46% in women aged ≤20 years.

  • 3

    Bacterial vaginosis (BV) and trichomonal vaginitis (TV) were associated with higher odds of hrHPV positivity in multivariable analyses.

  • 4

    BV and TV were linked to hrHPV12 positivity, while TV was specifically associated with HPV16/18 positivity.

  • 5

    The findings indicate age-specific distributions of hrHPV positivity and highlight the heterogeneity of associations across hrHPV genotype categories.

Original Source(s)

Associations between vaginal microecological status and high-risk human papillomavirus positivity in women from Eastern China: a retrospective cross-sectional study

  • by Junxia Wang, Xinyong Liu, Fangfei Liu, Juan Liu, Yan Zhao, Cuizhu Ma, Lina Wang, Xing Shi

  • July 10, 2026

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