Effects of Nd: YAG laser capsulotomy on central macular thickness: a systematic review and meta-analysis - Takeaways - MDSpire

Impact of Nd: YAG Laser Capsulotomy on Central Macular Thickness: A Systematic Review and Meta-Analysis

  • By

  • Yipeng Deng

  • Yanling Lu

  • Ying Liu

  • Yongran Li

  • July 21, 2026

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  • 1

    This systematic review and meta-analysis evaluates central macular thickness changes after Nd: YAG laser capsulotomy for posterior capsule opacification.

  • 2

    A total of 23 studies involving 1,762 eyes were analyzed, revealing significant increases in central macular thickness at postoperative week 1, month 1, and month 3.

  • 3

    No significant change in central macular thickness was observed at postoperative day 1, indicating a temporal pattern of thickness increases.

  • 4

    Subgroup analyses indicated that higher laser energy levels and poorer baseline visual acuity were associated with greater changes in central macular thickness.

  • 5

    The overall risk of bias in the included studies was considered moderate, with no significant publication bias identified.

Original Source(s)

Effects of Nd: YAG laser capsulotomy on central macular thickness: a systematic review and meta-analysis

  • by Yipeng Deng, Yanling Lu, Ying Liu, Yongran Li

  • July 21, 2026

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