Systemic immune-inflammation index predicts post-thrombectomy outcomes and reveals a mediating role in the association between neurocardiac stress and prognosis: a multicenter study - Takeaways - MDSpire

Systemic immune-inflammation index predicts post-thrombectomy outcomes and reveals a mediating role in the association between neurocardiac stress and prognosis: a multicenter study

  • By

  • Long Yang

  • Han Zhao

  • Qingtao Xie

  • Qitong Chen

  • Yehong Liu

  • Hailiang Li

  • Jun Lu

  • Bo Du

  • Jiheng Hao

  • Jiyou Yu

  • Chao Sun

  • Yu Liu

  • Yujia Zhai

  • Haibing Liao

  • Yiming Yin

  • Hui Chen

  • Qiuchen Zhao

  • Yu Feng

  • May 29, 2026

  • 0 min

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  • 1

    The study investigates the Systemic Immune-Inflammation Index (SII) as a predictor of outcomes following endovascular thrombectomy (EVT) in stroke patients.

  • 2

    A total of 678 EVT patients were screened, with 515 forming the derivation cohort, revealing a 56.1% rate of poor outcomes.

  • 3

    Atrial fibrillation with rapid ventricular response (AF-RVR) was found to correlate with elevated SII, significantly increasing the risk of poor outcomes.

  • 4

    Mediation analysis indicated that SII significantly accounted for part of the association between AF-RVR and poor functional outcomes.

  • 5

    The developed nomogram integrating AF-RVR and SII demonstrated good discrimination and clinical utility for predicting post-EVT outcomes.

Original Source(s)

Systemic immune-inflammation index predicts post-thrombectomy outcomes and reveals a mediating role in the association between neurocardiac stress and prognosis: a multicenter study

  • by Long Yang, Han Zhao, Qingtao Xie, Qitong Chen, Yehong Liu, Hailiang Li, Jun Lu, Bo Du, Jiheng Hao, Jiyou Yu, Chao Sun, Yu Liu, Yujia Zhai, Haibing Liao, Yiming Yin, Hui Chen, Qiuchen Zhao, Yu Feng

  • May 29, 2026

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