The appearance of “faggot Auer rods” in blasts of non-M3 acute myeloid leukemia - Takeaways - MDSpire

The appearance of “faggot Auer rods” in blasts of non-M3 acute myeloid leukemia

  • By

  • Cui Zhang

  • Jia Li

  • Wenfang Zhuang

  • June 8, 2026

  • 0 min

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  • 1

    A 79-year-old male was diagnosed with non-M3 acute myeloid leukemia (AML) after presenting with leukocytosis and elevated monocyte levels.

  • 2

    The patient's bone marrow aspirate revealed abnormal leukocytes with 'faggot-like' Auer bodies, which are typically associated with acute promyelocytic leukemia (APL).

  • 3

    Despite the presence of 'faggot-like' Auer rods, no APL-specific fusion genes were detected, leading to the diagnosis of non-M3 subtype AML.

  • 4

    The case highlights the diagnostic challenges in distinguishing non-APL AML from APL based solely on morphology.

  • 5

    This report emphasizes the importance of molecular testing for accurate diagnosis and management of acute myeloid leukemia.

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