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1
Paucibacillary tuberculous meningitis (TBM) can be diagnostically challenging, particularly when classical symptoms are absent and microbiological tests are negative.
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2
The Marais criteria provide a standardized framework for TBM diagnosis in clinical research, with a score of ≥6 required for possible TBM.
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3
A 63-year-old woman with motor deficits and seizures had meningeal biopsy findings and a positive interferon-gamma release assay that strongly supported a diagnosis of TBM.
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4
Despite complete symptomatic resolution, follow-up MRI showed radiological progression, demonstrating clinical-radiological dissociation.
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5
Anti-tuberculosis therapy lasted approximately 12 months; the patient achieved full neurological recovery, and no significant adverse events were reported during the documented 9-month treatment follow-up.
