Diurnal variation of wearable device-based heart rate variability in the Chronic Renal Insufficiency Cohort study - Takeaways - MDSpire

Diurnal variation of wearable device-based heart rate variability in the Chronic Renal Insufficiency Cohort study

  • By

  • Carsten Skarke

  • Wei Yang

  • Daohang Sha

  • Nicholas F. Lahens

  • Tamara Isakova

  • Mark Unruh

  • Rajat Deo

  • Eunice Carmona-Powell

  • John H. Holmes

  • Elaine Ficarra

  • Jing Chen

  • Jiang He

  • Hernan Rincon-Choles

  • Vallabh Shah

  • Chi-yuan Hsu

  • Amanda H. Anderson

  • James P. Lash

  • Mahboob Rahman

  • November 13, 2025

  • 0 min

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  • 1

    The study analyzed heart rate variability (HRV) in 458 chronic kidney disease participants using wearable BioPatch devices.

  • 2

    Diabetes was linked to a 7.4 ms reduction in Standard Deviation of NN Intervals (SDNN) compared to non-diabetic participants.

  • 3

    Higher proteinuria levels were associated with a 5.73 ms decrease in SDNN, indicating a relationship between kidney function and HRV.

  • 4

    The study represents the largest dataset evaluating SDNN in chronic kidney disease using wearable EKG technology.

  • 5

    Findings suggest that specific clinical factors significantly influence HRV, providing a basis for future cardiovascular risk assessments.

Original Source(s)

Diurnal variation of wearable device-based heart rate variability in the Chronic Renal Insufficiency Cohort study

  • by Carsten Skarke, Wei Yang, Daohang Sha, Nicholas F. Lahens, Tamara Isakova, Mark Unruh, Rajat Deo, Eunice Carmona-Powell, John H. Holmes, Elaine Ficarra, Jing Chen, Jiang He, Hernan Rincon-Choles, Vallabh Shah, Chi-yuan Hsu, Amanda H. Anderson, James P. Lash, Mahboob Rahman

  • November 13, 2025

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