Heart Failure is an Independent Risk Factor for Incident Hip, Proximal Humerus, and Wrist Fractures in a High-Risk Older Population - Takeaways - MDSpire
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Heart Failure as a Distinct Risk Factor for New Hip, Proximal Humerus, and Wrist Fractures in Older Adults at Elevated Risk

  • By

  • Amanda J. Chang

  • Alan S. Go

  • Malini Chandra

  • Laura D. Carbone

  • Howard A. Fink

  • Susan M. Ott

  • Joan C. Lo

  • January 26, 2026

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  • 1

    Heart failure (HF) significantly increases the risk of hip, proximal humerus, and wrist fractures in older adults initiating osteoporosis therapy.

  • 2

    In a study of 60,892 older adults, those with HF had a 40-50% higher risk of non-vertebral osteoporotic fractures compared to those without HF.

  • 3

    The study found that HF remains an independent fracture risk factor even among high-risk populations receiving bisphosphonate therapy.

  • 4

    Cumulative fracture incidence was significantly higher in adults with HF across all studied fracture sites, with p-values less than 0.001.

  • 5

    Identifying HF-specific mechanisms contributing to fracture risk is crucial for improving management strategies in older adults.

Original Source(s)

Heart Failure is an Independent Risk Factor for Incident Hip, Proximal Humerus, and Wrist Fractures in a High-Risk Older Population

  • by Amanda J. Chang, Alan S. Go, Malini Chandra, Laura D. Carbone, Howard A. Fink, Susan M. Ott, Joan C. Lo

  • January 26, 2026

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