Efficacy of intravenous parecoxib in preventing post-endoscopic retrograde cholangiopancreatography pancreatitis: a randomized controlled trial - Takeaways - MDSpire

Efficacy of intravenous parecoxib in preventing post-endoscopic retrograde cholangiopancreatography pancreatitis: a randomized controlled trial

  • By

  • Thanaput Kunlayawutipong

  • Tummarong Charoenrit

  • Tanawat Jongraksak

  • Thanawin Wong

  • Nisa Netinatsunton

  • Siriboon Attasaranya

  • Thanapon Yaowmaneerat

  • Jaksin Sottisuporn

  • Suraphon Assawasuwannakit

  • Siwanon Nawalerspanya

  • Surawitch Sawathanon

  • Pimsiri Sripongpun

  • Tanawat Pattarapuntakul

  • February 23, 2026

  • 0 min

Share

  • 1

    Intravenous parecoxib is a selective COX-2 inhibitor that may effectively reduce the incidence of post-ERCP pancreatitis (PEP).

  • 2

    The study was a double-blind, randomized controlled trial involving patients undergoing their first therapeutic ERCP at Songklanagarind Hospital.

  • 3

    Patients were classified as high or low risk for PEP based on specific criteria, including sex, history of pancreatitis, and age.

  • 4

    Results indicated that intravenous parecoxib significantly reduced post-ERCP abdominal pain compared to standard hydration alone.

  • 5

    The study's findings support the potential use of intravenous parecoxib as a preventive intervention for PEP in ERCP patients.

Original Source(s)

Efficacy of intravenous parecoxib in preventing post-endoscopic retrograde cholangiopancreatography pancreatitis: a randomized controlled trial

  • by Thanaput Kunlayawutipong, Tummarong Charoenrit, Tanawat Jongraksak, Thanawin Wong, Nisa Netinatsunton, Siriboon Attasaranya, Thanapon Yaowmaneerat, Jaksin Sottisuporn, Suraphon Assawasuwannakit, Siwanon Nawalerspanya, Surawitch Sawathanon, Pimsiri Sripongpun, Tanawat Pattarapuntakul

  • February 23, 2026

Related Content

Clinical Evaluation of the Peripheral Perfusion Index as a Predictor of Femoral Nerve Block Efficacy in Unilateral Arthroscopic Meniscal Surgery

Comorbidities Worsen Carpal Tunnel Outcomes

Patients with systemic diseases had worse symptoms and function before and following surgery, though improvement after release was similar.

Lumbar Fusion: Two Decades of Change

Investigators find rising use of complex lumbar fusion procedures and increasing hospital costs in the US.