Long-term Impact of Intravitreal Injections on the ocular surface; a 2-year follow-up study - Takeaways - MDSpire

Two-Year Evaluation of Ocular Surface Effects Following Intravitreal Injections

  • By

  • Agni Malmin

  • Markus Vicente Tørud Olsen

  • Vilde Marie Thomseth

  • Inga-Britt Kjellevold Haugen

  • Tor Paaske Utheim

  • Vegard Asgeir Forsaa

  • July 17, 2026

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  • 1

    Intravitreal injection therapy is the most common intraocular procedure, using topical povidone-iodine as the standard antiseptic.

  • 2

    The study evaluated ocular surface parameters in patients with neovascular age-related macular degeneration over two years.

  • 3

    Significant increases in bulbar redness were observed in untreated fellow eyes compared to baseline measurements.

  • 4

    Both treated and untreated eyes showed significant meibomian gland loss after two years of serial intravitreal injections.

  • 5

    The study suggests a potential beneficial alteration of the ocular surface microbiome due to povidone-iodine or anti-VEGF therapy.

Original Source(s)

Long-term Impact of Intravitreal Injections on the ocular surface; a 2-year follow-up study

  • by Agni Malmin, Markus Vicente Tørud Olsen, Vilde Marie Thomseth, Inga-Britt Kjellevold Haugen, Tor Paaske Utheim, Vegard Asgeir Forsaa

  • July 17, 2026

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