Necrotizing enterocolitis: risk factors and predictive modeling in a cohort of preterm infants. A case-control study - Takeaways - MDSpire

Necrotizing enterocolitis: risk factors and predictive modeling in a cohort of preterm infants. A case-control study

  • By

  • T. Pérez-Oliver

  • A. Pinilla-Gonzalez

  • M. Gormaz

  • J. Kuligowski

  • E. Serna

  • L. Torrejón-Rodríguez

  • I. Lara-Cantón

  • A. Cayuela-Hernández

  • M. Vento

  • A. Parra-Llorca

  • M. Cernada

  • July 16, 2026

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  • 1

    Necrotizing enterocolitis (NEC) is a significant cause of morbidity and mortality in very preterm infants.

  • 2

    The study identified several risk factors for NEC, including lower gestational age, birth weight, and prolonged rupture of membranes.

  • 3

    Early intravenous antibiotic administration and placental abruption were found to be independent risk factors for NEC.

  • 4

    A predictive model for NEC demonstrated moderate discriminatory ability with an AUC of 0.73.

  • 5

    Further multicenter studies are needed to validate the predictive tool and assess its clinical utility.

Original Source(s)

Necrotizing enterocolitis: risk factors and predictive modeling in a cohort of preterm infants. A case-control study

  • by T. Pérez-Oliver, A. Pinilla-Gonzalez, M. Gormaz, J. Kuligowski, E. Serna, L. Torrejón-Rodríguez, I. Lara-Cantón, A. Cayuela-Hernández, M. Vento, A. Parra-Llorca, M. Cernada

  • July 16, 2026

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