Imaging-based techniques for ablation zone definition and volumetry after laser interstitial thermal therapy (LITT) for intracranial lesions: a systematic review - Takeaways - MDSpire

Imaging-based techniques for ablation zone definition and volumetry after laser interstitial thermal therapy (LITT) for intracranial lesions: a systematic review

  • By

  • Céline L. G. Neutel

  • Thomas M. Putinela

  • Maroeska M. Rovers

  • Pierre A. Robe

  • Mark ter Laan

  • Christiaan G. Overduin

  • October 8, 2025

  • 0 min

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  • 1

    Laser interstitial thermal therapy (LITT) is a minimally invasive technique for treating various intracranial lesions.

  • 2

    The extent of ablation (EOA) is linked to improved prognosis in LITT, highlighting the importance of accurate ablation zone definition.

  • 3

    Post-LITT ablation zones are typically visualized using contrast-enhanced T1-weighted MRI, but accurate delineation can be challenging.

  • 4

    This systematic review evaluates imaging-based methods for defining and measuring the ablation zone after LITT in intracranial lesions.

  • 5

    The review aims to inform the development of standardized imaging-based outcome measures following LITT procedures.

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