EASIX as a moderately effective prognostic marker for mortality in severe acute pancreatitis: a retrospective study - Takeaways - MDSpire

EASIX as a moderately effective prognostic marker for mortality in severe acute pancreatitis: a retrospective study

  • By

  • Lvyuan Shi

  • Lili Cao

  • Dingyuan Wan

  • Lietao Wang

  • Ping Li

  • Siyuan Chen

  • Zhongwei Zhang

  • Min He

  • July 7, 2026

  • 0 min

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  • 1

    EASIX is calculated using LDH, creatinine, and platelet count to assess endothelial activation and stress in severe acute pancreatitis patients.

  • 2

    In a study of 340 patients, the overall mortality rate for severe acute pancreatitis was found to be 28.82%.

  • 3

    EASIX levels were significantly higher in non-survivors compared to survivors, indicating its potential as a mortality predictor.

  • 4

    The predictive model incorporating EASIX and other factors achieved an AUC of 0.77, outperforming EASIX alone with an AUC of 0.70.

  • 5

    The study suggests that while EASIX is a moderately effective prognostic marker, external validation is necessary before clinical application.

Original Source(s)

EASIX as a moderately effective prognostic marker for mortality in severe acute pancreatitis: a retrospective study

  • by Lvyuan Shi, Lili Cao, Dingyuan Wan, Lietao Wang, Ping Li, Siyuan Chen, Zhongwei Zhang, Min He

  • July 7, 2026

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