Dialysis May Improve Caffeine Intoxication Outcomes

Case analysis links severe symptoms to prognosis and highlights management patterns of high-dose exposures

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Severe caffeine intoxication can lead to life-threatening complications, with extracorporeal blood purification linked to improved survival.
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The review analyzed 216 cases of caffeine intoxication from 1883 to 2023, revealing a median ingestion of 12 g and median serum concentration of 160 mg/L.
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Tachycardia was present in 87% of patients, with convulsions in 18%, and worse outcomes were associated with greater symptom severity.
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Extracorporeal blood purification was used in 28% of cases, leading to a higher survival rate of 95% compared to 73% in those not treated this way.
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The study noted limitations such as retrospective design and incomplete data, emphasizing that no definitive treatment recommendations can be made.

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