Triglyceride-glucose index as predictor of gestational diabetes mellitus in early pregnancy: a prospective cohort study - Takeaways - MDSpire

Triglyceride-glucose index as predictor of gestational diabetes mellitus in early pregnancy: a prospective cohort study

  • By

  • Ge Huang

  • Meng Su

  • Cheng Li

  • Hongzhuan Tan

  • Jing Deng

  • Mengshi Chen

  • June 29, 2026

  • 0 min

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  • 1

    The study enrolled 870 pregnant women to investigate the association between triglyceride-glucose (TyG) levels and gestational diabetes mellitus (GDM).

  • 2

    The incidence rate of GDM among participants was 13.68%, with 119 women developing the condition during the study.

  • 3

    Elevated TyG levels in early and mid-pregnancy, as well as a significant increase in TyG levels, were identified as independent risk factors for GDM.

  • 4

    Multivariate Cox regression analysis adjusted for confounding factors confirmed that mid-pregnancy TyG levels posed the highest risk for GDM.

  • 5

    The findings suggest that monitoring TyG indices during pregnancy may provide valuable insights for early prevention and management of GDM.

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