The Association Between Physical Activity and the Incidence of Cataract and Age-Related Macular Degeneration: A Systematic Review and Meta-Analysis of Cohort Studies - Takeaways - MDSpire
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The Association Between Physical Activity and the Incidence of Cataract and Age-Related Macular Degeneration: A Systematic Review and Meta-Analysis of Cohort Studies

  • By

  • Dagfinn Aune

  • Ahmad Jayedi

  • Asma Kazemi

  • Sepideh Soltani

  • Fatemeh Rezaei

  • Michael F. Leitzmann

  • March 11, 2026

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  • 1

    Cataract and age-related macular degeneration are leading causes of global blindness, affecting millions worldwide.

  • 2

    Physical activity may reduce the risk of cataract and age-related macular degeneration, but studies show mixed results.

  • 3

    Major risk factors for cataract include diabetes, hypertension, and smoking, while age-related macular degeneration shares similar risk factors.

  • 4

    A systematic review and meta-analysis were conducted to clarify the association between physical activity and these eye conditions.

  • 5

    The study quality of included research was assessed using a modified Newcastle-Ottawa scale to ensure reliability of findings.

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