Ultra-early neurological pupil index trajectories and clinical outcomes in acute brain injury - Takeaways - MDSpire

Ultra-early neurological pupil index trajectories and clinical outcomes in acute brain injury

  • By

  • Yong Soo Kim

  • Dong-Wan Kang

  • Hyung Seok Guk

  • Museong Kim

  • Heewon Jeong

  • Huimahn Alex Choi

  • Sung-Min Cho

  • Moon-Ku Han

  • Hee Eun Kim

  • Dong Keon Lee

  • Han-Gil Jeong

  • June 12, 2026

  • 0 min

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  • 1

    The study analyzed ultra-early pupillometry indices in patients with acute brain injury to predict clinical outcomes.

  • 2

    NPi trajectories categorized into four groups showed significant differences in ICU mortality rates among patients.

  • 3

    The Worsened and Consistently low NPi groups had higher ICU mortality compared to the Consistently high group.

  • 4

    Incorporating NPi trajectories improved predictive accuracy for ICU mortality and functional outcomes compared to clinical variables alone.

  • 5

    Automated pupillometry provides a reliable, quantitative measure of pupillary reactivity in the hyperacute phase of brain injury.

Original Source(s)

Ultra-early neurological pupil index trajectories and clinical outcomes in acute brain injury

  • by Yong Soo Kim, Dong-Wan Kang, Hyung Seok Guk, Museong Kim, Heewon Jeong, Huimahn Alex Choi, Sung-Min Cho, Moon-Ku Han, Hee Eun Kim, Dong Keon Lee, Han-Gil Jeong

  • June 12, 2026

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