Preoperative Enterosignatures Predict Surgical Site Infections After Abdominal Surgery - Takeaways - MDSpire

Preoperative Enterosignatures Predict Surgical Site Infections After Abdominal Surgery

  • By

  • Simone N Zwicky

  • Daniel Spari

  • Daniel Rodjakovic

  • Hugo Guillen-Ramirez

  • Bahtiyar Yilmaz

  • Guido Beldi

  • September 3, 2025

  • 0 min

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  • 1

    Preoperative intestinal microbiota profiles can predict the risk of surgical site infections (SSIs) following abdominal surgery.

  • 2

    The study identified five enterosignatures (ESs) that simplify complex microbial compositions into generalizable patterns.

  • 3

    The Firmicutes ES was linked to a higher risk of SSIs, while the Prevotella ES was associated with a reduced risk.

  • 4

    The Firmicutes-to-Prevotella ES ratio was a significant independent predictor of SSIs, with a strong association confirmed by statistical models.

  • 5

    This research highlights the potential of using preoperative microbiota profiles as biomarkers to identify high-risk surgical patients.

Original Source(s)

Preoperative Enterosignatures Predict Surgical Site Infections After Abdominal Surgery

  • by Simone N Zwicky, Daniel Spari, Daniel Rodjakovic, Hugo Guillen-Ramirez, Bahtiyar Yilmaz, Guido Beldi

  • September 3, 2025

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