Urinary Fatty Acid Binding Protein 2 (FABP2) as a Biomarker of Intestinal Injury in Pediatric Celiac Disease - Takeaways - MDSpire

Urinary Fatty Acid Binding Protein 2 (FABP2) as a Biomarker of Intestinal Injury in Pediatric Celiac Disease

  • By

  • Mehta, Vijay

  • Kapoor, Nidhi

  • Milliron, Chloe

  • Stoeckel, Noah

  • Ballelos, Edwin

  • Tiqui, Katrina

  • Deb, Chirajyoti

  • Abomoelak, Bassam

  • Schreck, Mary

  • Mehta, Devendra

  • May 20, 2026

  • 0 min

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  • 1

    Celiac disease is an autoimmune enteropathy triggered by gluten, leading to intestinal damage and impaired gut barrier integrity.

  • 2

    Urinary fatty acid-binding protein 2 (FABP2) may serve as a non-invasive biomarker for assessing intestinal integrity in pediatric patients.

  • 3

    In a study of 103 pediatric patients, FABP2 levels were significantly higher in active celiac disease patients compared to controls.

  • 4

    FABP2 levels were not significantly elevated in celiac disease patients on a gluten-free diet for over six months.

  • 5

    The study suggests that urinary FABP2 could reflect intestinal injury, but further research is needed to confirm its diagnostic utility.

Original Source(s)

Urinary Fatty Acid Binding Protein 2 (FABP2) as a Biomarker of Intestinal Injury in Pediatric Celiac Disease

  • by Mehta, Vijay , Kapoor, Nidhi , Milliron, Chloe , Stoeckel, Noah , Ballelos, Edwin , Tiqui, Katrina , Deb, Chirajyoti , Abomoelak, Bassam , Schreck, Mary , Mehta, Devendra

  • May 20, 2026

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