Impulse oscillometry values calibrated against spirometric obstruction in children with suspected asthma - Takeaways - MDSpire

Impulse oscillometry values calibrated against spirometric obstruction in children with suspected asthma

  • By

  • Liang-Mei Lin

  • Yi-Giien Tsai

  • Yu-Jun Chang

  • Jeffrey Eli Whang

  • Ming-Sheng Lee

  • June 8, 2026

  • 0 min

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  • 1

    The study enrolled 722 children aged 6–18 years with suspected asthma to compare impulse oscillometry (IOS) and spirometry for assessing airway obstruction.

  • 2

    IOS parameters R5, X5, AX, Fres, and R5–R20 were recorded, with R5−R20 showing the strongest correlation with spirometric measures of obstruction.

  • 3

    Cutoff values for IOS parameters were established, with AX and Fres showing predictive accuracies of 62.2% and 60.2% in younger children after bronchodilation.

  • 4

    In older children, a 20% decrease in Fres and a 40% decrease in AX predicted obstructive lung disease with accuracies of 73.2% and 75.7%, respectively.

  • 5

    The study aims to guide future IOS guidelines and assist pediatricians in assessing lower airway obstruction in asthmatic children.

Original Source(s)

Impulse oscillometry values calibrated against spirometric obstruction in children with suspected asthma

  • by Liang-Mei Lin, Yi-Giien Tsai, Yu-Jun Chang, Jeffrey Eli Whang, Ming-Sheng Lee

  • June 8, 2026

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