Ventricular Strain and Correlation with Cardiovascular Symptoms and Pulmonary Function Testing in Pediatric Patients with a History of COVID-19: Results from the Pediatric SARS-CoV-2 Long Term Outcomes Study - Takeaways - MDSpire
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Ventricular Strain and Its Relationship with Cardiovascular Symptoms and Pulmonary Function in Children with Previous COVID-19: Findings from the Pediatric SARS-CoV-2 Long-Term Outcomes Study

  • By

  • Michael He

  • Thomas R. Burklow

  • Craig A. Sable

  • Stephanie R. Lacey

  • James E. Bost

  • Andrew J. Lipton

  • Anastassios C. Koumbourlis

  • Maggie E.S. Curry

  • Farokh Choodar

  • Malgorzata Lasota

  • Suhyoun Park

  • Mistir Dubale

  • Michael DiMaggio

  • Kevin B. Rubenstein

  • Karyl Barron

  • Gina A. Montealegre Sanchez

  • Roberta L. DeBiasi

  • Ashraf S. Harahsheh

  • July 2, 2026

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  • 1

    The Pediatric COVID-19 Outcomes Study assessed the long-term impact of COVID-19 in patients aged 0 to 21 years.

  • 2

    Of 852 participants completing baseline visits, 830 were analyzed: 683 infected and 147 uninfected. Twelve-month follow-up included 550 infected and 121 initially uninfected participants.

  • 3

    Cardiac function did not differ between infected and uninfected participants at baseline or 12-month follow-up.

  • 4

    Participants with obstructive pulmonary function test results had less negative right ventricular free-wall longitudinal strain at baseline and 12 months.

  • 5

    Infected participants frequently reported cardiac, constitutional, and respiratory symptoms, but ventricular strain measures did not differ between those with and without symptoms.

Original Source(s)

Ventricular Strain and Correlation with Cardiovascular Symptoms and Pulmonary Function Testing in Pediatric Patients with a History of COVID-19: Results from the Pediatric SARS-CoV-2 Long Term Outcomes Study

  • by Michael He, Thomas R. Burklow, Craig A. Sable, Stephanie R. Lacey, James E. Bost, Andrew J. Lipton, Anastassios C. Koumbourlis, Maggie E.S. Curry, Farokh Choodar, Malgorzata Lasota, Suhyoun Park, Mistir Dubale, Michael DiMaggio, Kevin B. Rubenstein, Karyl Barron, Gina A. Montealegre Sanchez, Roberta L. DeBiasi, Ashraf S. Harahsheh

  • July 2, 2026

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