Admission hyperglycemia, estimated glomerular filtration rate and outcome of acute ischemic stroke after mechanical thrombectomy: a mediation analysis

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Admission hyperglycemia is significantly associated with poorer long-term functional outcomes after mechanical thrombectomy in acute ischemic stroke patients.
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Lower postoperative estimated glomerular filtration rate (post-eGFR) correlates with a decreased likelihood of achieving a good outcome at 6 months.
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Mediation analysis indicates that postoperative renal function accounts for 25.57% of the total effect of admission hyperglycemia on outcomes.
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The study included 397 patients, with 49.9% experiencing admission hyperglycemia and only 38.0% achieving a good outcome at 6 months.
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Understanding the relationship between admission hyperglycemia, renal function, and outcomes can help optimize treatment strategies for acute ischemic stroke.

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