Therapeutic apheresis may reduce circulating PFAS and microplastic-related signals, according to preliminary data from Technische Universität Dresden.
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In a study of 34 patients, significant reductions in C-reactive protein, fibrinogen, LDL cholesterol, and lipoprotein(a) were observed after double filtration plasmapheresis.
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Liquid chromatography-tandem mass spectrometry revealed up to 25% reductions in PFAS levels in samples from 14 patients after treatment.
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Pyrolysis gas chromatography-mass spectrometry indicated decreases in polyethylene and polyvinyl chloride in blood samples from treated patients.
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The findings are preliminary, and the study does not confirm a shared clearance mechanism or resolve challenges in measuring microplastics in blood.
