Intraoperative integration of nTMS, CCEPs and DCS for language. A glance to the next future? - Takeaways - MDSpire

Intraoperative integration of nTMS, CCEPs and DCS for language. A glance to the next future?

  • By

  • Camilla Bonaudo

  • Riccardo Carrai

  • Edoardo Pieropan

  • Francesca Fedi

  • Eleonora Visocchi

  • Fabrizio Baldanzi

  • Francesca Battista

  • Antonello Grippo

  • Alessandro Della Puppa

  • October 3, 2025

  • 0 min

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  • 1

    The integration of navigated Transcranial Magnetic Stimulation (nTMS), Cortico-Cortical Evoked Potentials (CCEPs), and Direct Cortical Stimulation (DCS) enhances language monitoring.

  • 2

    Awake surgery remains the gold standard for intraoperative language testing, allowing real-time assessment of linguistic functions during tumor resection.

  • 3

    A case study involving a 32-year-old female patient demonstrated the successful application of combined nTMS, CCEPs, and DCS for precise language mapping.

  • 4

    Statistical analysis showed a minimal average distance of 5.10 mm between nTMS, DCS, and CCEPs spots, indicating high spatial accuracy in language circuit mapping.

  • 5

    Postoperative outcomes were satisfactory, with no complications reported, highlighting the potential of these integrated techniques for improved surgical results.

Original Source(s)

Intraoperative integration of nTMS, CCEPs and DCS for language. A glance to the next future?

  • by Camilla Bonaudo, Riccardo Carrai, Edoardo Pieropan, Francesca Fedi, Eleonora Visocchi, Fabrizio Baldanzi, Francesca Battista, Antonello Grippo, Alessandro Della Puppa

  • October 3, 2025

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